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CP-724714 (b)

CAS No. 537705-08-1

CP-724714 (b)( —— )

Catalog No. M14915 CAS No. 537705-08-1

CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM.

Purity : >98% (HPLC)

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Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

CP-724714 (b)
Note

Research use only, not for human use.
Brief Description

CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM.
Description

CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM, >640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met etc in cell-free assays. Phase 2.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

EGFR
Recptor

HER2/ErbB2
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

537705-08-1
Formula Weight

469.53
Molecular Formula

C27H27N5O3
Purity

>98% (HPLC)
Solubility

N/A
SMILES

CCOC(=O)NC/C=C/C1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OC4=CN=C(C=C4)C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1 Jani JP, et al. Cancer Res, 2007, 67(20), 9887-9893. 2 Feng B, et al. Toxicol Sci, 2009, 108(2), 492-500.

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